Alpha-fetoprotein, Non-pregnancy (NP-AFP)

Prenatal Screening Laboratory

Immunoassay

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Specimen Required:

Serum: Adult 2 mL,   Infant 0.5 mL

Room temperature or 4°C

Days Test Set Up:

Monday - Friday

Analytic Time:

48 hours

Reference Values:

Adult: <10 IU/mL = Normal

Infant: varies with age (reference intervals from birth to age 2 provided with report).

CPT Code(s):

82105

Relevance:

Elevated AFP is associated with certain germ cell tumors including some forms of hepatoma, testicular tumor, and ovarian tumor in non-pregnant individuals. AFP levels are also used to monitor suspected hepatic dysfunction such as cirrhosis or newborn tyrosinemia

Reference(s)

• Böhme MEG, Vesterling - Horner D, Calaminus G, Gobel U: Alpha 1-fetoprotein (AFP) reference values in infants up to 2 years of age. Pediatr Hemato Oncol, 15(2):135-142, Mar-Apr 1998 .